![]() ![]() TRELEGY should be used with caution in patients with cardiovascular disorders, especially coronary insufficiency, cardiac arrhythmias, and hypertension. If such effects occur, TRELEGY may need to be discontinued. Vilanterol can produce clinically significant cardiovascular effects in some patients as measured by increases in pulse rate, systolic or diastolic blood pressure, and also cardiac arrhythmias, such as supraventricular tachycardia and extrasystoles.Discontinue TRELEGY if such reactions occur. Hypersensitivity reactions such as anaphylaxis, angioedema, rash, and urticaria may occur after administration of TRELEGY. ![]() If paradoxical bronchospasm occurs, discontinue TRELEGY and institute alternative therapy. ![]()
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